Scientific Literature on PCA3

Following is a list of PCA3 literature and presentations, which we regularly update. You may access scientific papers abstracts and publications by clicking on the link, when available.

Scientific Papers

  1. Nakanishi, H. et al, PCA3 Molecular Urine Assay Correlates With Prostate Cancer Tumor
    Volume: Implication in Selecting Candidates for Active Surveillance    , The Journal of Urology, 2008 May;179(5):1804-9
  2. Deras, IL et al., PCA3: a molecular urine assay for predicting prostate biopsy outcome, The Journal of Urology, 2008 Apr;179(4):1587-92
  3. Shappell, S.B., Clinical Utility of Prostate Carcinoma MolecularDiagnostic Tests, Reviews in Urology, 2008;10(1):44-69
  4. Popa, Ion et al., Identification of PCA3 (DD3) in prostatic carcinoma by in situ hybridization, Modern Pathology, 2007 Nov;20(11):1121-7
  5. Marks, L.S. et al., PCA3 Molecular Urine Assay for Prostate Cancer in Men Undergoing Repeat Biopsy, Urology, 69(3): 532-535, March 2007
  6. Fradet, Y. et al, uPM3, A New Molecular Urine Test for the Detection of Prostate Cancer, Urology 64 (2): 311-316, August, 2004
  7. Tinzl, M. et al, DD3PCA3 RNA Analysis in Urine – A New Perspective for Detecting Prostate Cancer, European Urology, Vol. 46(2), pages 182-187, August 2004
  8. Schalken, JA et al, New Targets for Therapy in Prostate Cancer: Differential Display Code 3 (DD3PCA3), a Highly Prostate Cancer-Specific Gene, Urology, 62 (5 Suppl 1):34-43, November 2003
  9. Hessels, D. et al., DD3PCA3-Based Molecular Urine Analysis for the Diagnosis of Prostate Cancer, European Urology, Vol. 44(1), pages 8-16, July 2003
  10. Leff, DN, Front-Running DD3PCA3 Gene Faced Off PSA Test of Prostate Carcinoma in First-Shot Urology Clinic Line-Up, BioWorld Today, July 10, 2003
  11. deKok, J. et al, DD3PCA3, a Very Sensitive and Specific Marker to Detect Prostate Tumors, Cancer Research, vol. 62, pages 2695-2698, May 2002
  12. Bussemakers, M. et al, DD3: A New Prostate-Specific Gene, Highly Overexpressed in Prostate Cancer, Cancer Research, Vol. 59, pages 5975-5979, December 1999

Posters and Presentations

  1. Schalken, J., PCA3 Is a Novel Genetic Marker, EAU Congress News, p. 17, March 23, 2007
  2. Groskopf, J. et al., The PCA3 Score is Independent of Prostate Gland Volume, and can Synergize with other Patient Information for Predicting Biopsy Outcome, EAU, March 2007
  3. Haese, A. et al, The Value of the PCA3 Assay in Guiding Decision Which Men With a Negative Prostate Biopsy Need Immediate Repeat Biopsy: Preliminary European Data, EAU, March 2007
  4. Nakanishi, H. et al, The Relationship Between PCA3 Score and Tumor Volume in Prostatectomy Samples, EAU, March 2007
  5. Overmyer, M., New PCa Assay Aids Critical Diagnostic Decisions, Urology Times, July 2006
  6. Fradet, Y. et al, PCA3 Molecular Urine Test: Development of a Method to Aid in Prostate Cancer Diagnosis, AUA, May 2006
  7. Marks, L.S. et al, Specificity of the PCA3 Molecular Urine Test for Prostate Cancer, AUA, May 2006
  8. Fradet, Y. et al, Performance of the PCA3 Urine Test on Subjects with Previous Negative Prostate Biopsies, AUA, May 2006
  9. Groskopf, J. et al, PCA3 Molecular Urine Assay: Characterization of a Method to Aid in the Diagnosis of Prostate Cancer, AUA, May 2006
  10. Bostwick, DG, PCA3Plus™: The Next Generation Genetic Test for Prostate Cancer Risk, AUA, May 2006
  11. Têtu, B. et al, PCA3DD3 Gene Expression is a Marker of Prostate Cancer, USCAP February 2005