Documentation scientifique sur le PCA3

Vous trouverez ci-dessous une liste des articles et présentations scientifiques sur le PCA3 et la prostate, mise à jour de façon régulière. Vous pouvez consulter les résumés de ces articles scientifiques ou les présentations en cliquant sur les liens fournis, lorsque disponibles.

Articles scientifiques

  1. Auprich M, et al, External Validation of Urinary PCA3-Based Nomograms to Individually Predict Prostate Biopsy Outcome, Eur Urol. 2010 Jul 3
  2. R. S. Rittmaster, et al, Predictive value of PCA3 for prostate biopsy outcome in men receiving dutasteride: Results from the dutasteride REDUCE trial, 2010 Genitourinary Cancers Symposium (ASCO), March 2010
  3. J. Groskopf, et al, Validation of the PCA3 molecular urine test for predicting repeat prostate biopsy outcome in the placebo arm of the dutasteride REDUCE trial, 2010 Genitourinary Cancers Symposium (ASCO), March 2010
  4. Schilling D et al, The Prostate Cancer gene 3 assay: indications for use in clinical practice, BJU Int. 2009 Nov 20.
  5. David P. Wood, MD, IPF 2009 - Do we need new markers in prostate cancer? - Session Highlights, UroToday, October 22, 2009
  6. Cheryl Guttman et al, PCA3: Predictive performance superior to PSA, fPSA, Urology Times, Oct 1, 2009
  7. Scott B. Shapell, MD PHD, Leonard S. Marks, MD, Clinical use of urine PCA3 mRNA testing, Urology Times, Sep 1, 2009
  8. Daphne Hessels et al, The use of PCA3 in the diagnosis of prostate cancer, Nature Reviews Urology 6 , 255-261 (May 2009)
  9. Fradet, Yves, Biomarkers in prostate cancer diagnosis and prognosis: beyond prostate-specific antigen, Current Opinion in Urology, 2009 May;19 (3):243-6
  10. Gerald L. Andriole, M.D. et al, Mortality Results from a Randomized Prostate-Cancer Screening Trial, The New England Journal of Medicine, Volume 360:1310-1319, March 26, 2009, Number 13
  11. Chunk FK et al, Prostate Cancer Gene 3 (PCA3): Development and Internal Validation of a Novel Biopsy Nomogram, European Urology., 2009 Mar 13
  12. Kirby RS et al, Prostate cancer diagnosis in the new millennium: strengths and weaknesses of prostate-specific antigen and the discovery and clinical evaluation of prostate cancer gene 3 (PCA3), BJU Int. 2009 Feb;103(4):441-5. Epub 2009 Jan 9

  13. Shappell, SB et al, PCA3 urine mRNA testing for prostate carcinoma: patterns of use by community urologists and assay performance in reference laboratory setting, J. Urol. 2009 Feb;73(2):363-8

  14. Whitman, E.J. et al, PCA3 Score Before Radical Prostatectomy Predicts Extracapsular Extension and Tumor Volume, The Journal of Urology, 2008 November, 180(5) : 1975-1979
  15. Ankerst, D.P. et al, Predicting Prostate Cancer Risk Through Incorporation of Prostate Cancer Gene 3, The Journal of Urology, 2008 October; 180(4) : 1303-1308
  16. van Gils MP et al, Detailed analysis of histopathological parameters in radical prostatectomy specimens and PCA3 urine test results, The Prostate 2008 Aug 1;68(11):1215-22
  17. Marks LS et al, Prostate Cancer Specificity of PCA3 Gene Testing: Examples from Clinical Practice, Reviews in Urology 2008 Summer;10(3):175-81
  18. Sokoll LJ, et al, A multicenter evaluation of the PCA3 molecular urine test: Pre-analytical effects, analytical performance, and diagnostic accuracy, Clinica Chimica Acta 2008; 389:1-6

  19. Haese, A. et al, Clinical utility of the PCA3 Urine Assay in European Men Scheduled for Repeat Biopsy, European Urology (2008), doi: 10.1016/j.eururo.2008.06.071

  20. Nakanishi, H. et al, PCA3 Molecular Urine Assay Correlates With Prostate Cancer Tumor
    Volume: Implication in Selecting Candidates for Active Surveillance    , The Journal of Urology, 2008 May;179(5) : 1804-9
  21. Deras, IL et al., PCA3: a molecular urine assay for predicting prostate biopsy outcome, The Journal of Urology, 2008 Apr;179(4) : 1587-92
  22. Shappell, S.B., Clinical Utility of Prostate Carcinoma MolecularDiagnostic Tests, Reviews in Urology, 2008;10(1):44-69
  23. Popa, Ion et al., Identification of PCA3 (DD3) in prostatic carcinoma by in situ hybridization, Modern Pathology, 2007 Nov;20(11) : 1121-7
  24. Jonathan L Wright et al, Newer Potential Biomarkers in Prostate Cancer, Reviews Urology 2007 Fall; 9(4): 207–213
  25. De la Taille A., ProgensaTM PCA3 test for prostate cancer detection, Expert Rev Mol Diagn 2007;7:491-7
  26. van Gils MP et al, Molecular PCA3 diagnostics on prostatic fluid, The Prostate, Volume 67, Issue 8, 881-887
  27. Reynolds, MA et al, Molecular markers for prostate cancer, Cancer Lett. 2007 Apr 28;249(1):5-13
  28. Marks, L.S. et al., PCA3 Molecular Urine Assay for Prostate Cancer in Men Undergoing Repeat Biopsy, Urology, 69(3): 532-535, mars 2007
  29. Fradet, Y. et al, uPM3, A New Molecular Urine Test for the Detection of Prostate Cancer, Urology 64 (2): 311-316, août 2004
  30. Tinzl, M. et al, DD3PCA3 RNA Analysis in Urine – A New Perspective for Detecting Prostate Cancer, European Urology, Vol. 46(2), pages 182-187, août 2004
  31. Schalken, JA et al, New Targets for Therapy in Prostate Cancer: Differential Display Code 3 (DD3PCA3), a Highly Prostate Cancer-Specific Gene, Urology, 62 (5 Suppl 1):34-43, novembre 2003
  32. Hessels, D. et al., DD3PCA3-Based Molecular Urine Analysis for the Diagnosis of Prostate Cancer, European Urology, Vol. 44(1), pages 8-16, juillet 2003
  33. Leff, DN, Front-Running DD3PCA3 Gene Faced Off PSA Test of Prostate Carcinoma in First-Shot Urology Clinic Line-Up, BioWorld Today, juillet 10, 2003
  34. deKok, J. et al, DD3PCA3, a Very Sensitive and Specific Marker to Detect Prostate Tumors, Cancer Research, vol. 62, pages 2695-2698, mai 2002
  35. Bussemakers, M. et al, DD3: A New Prostate-Specific Gene, Highly Overexpressed in Prostate Cancer, Cancer Research, Vol. 59, pages 5975-5979, décembre 1999

Présentations

  1. Schalken, J., PCA3 Is a Novel Genetic Marker, EAU Congress News, p. 17, 23 mars 2007
  2. Groskopf, J. et al., The PCA3 Score is Independent of Prostate Gland Volume, and can Synergize with other Patient Information for Predicting Biopsy Outcome, EAU, mars 2007
  3. Haese, A. et al, The Value of the PCA3 Assay in Guiding Decision Which Men With a Negative Prostate Biopsy Need Immediate Repeat Biopsy: Preliminary European Data, EAU, mars 2007
  4. Nakanishi, H. et al, The Relationship Between PCA3 Score and Tumor Volume in Prostatectomy Samples, EAU, mars 2007
  5. Overmyer, M., New PCa Assay Aids Critical Diagnostic Decisions, Urology Times, juillet 2006
  6. Fradet, Y. et al, PCA3 Molecular Urine Test: Development of a Method to Aid in Prostate Cancer Diagnosis, AUA, mai 2006
  7. Marks, L.S. et al, Specificity of the PCA3 Molecular Urine Test for Prostate Cancer, AUA, mai 2006
  8. Fradet, Y. et al, Performance of the PCA3 Urine Test on Subjects with Previous Negative Prostate Biopsies, AUA, mai 2006
  9. Groskopf, J. et al, PCA3 Molecular Urine Assay: Characterization of a Method to Aid in the Diagnosis of Prostate Cancer, AUA, mai 2006
  10. Bostwick, DG, PCA3Plus™: The Next Generation Genetic Test for Prostate Cancer Risk, AUA, mai 2006
  11. Têtu, B. et al, PCA3DD3 Gene Expression is a Marker of Prostate Cancer, USCAP, février 2005